| Characteristic | Details |
|---|---|
| Active Ingredient | Vardenafil 20mg |
| Formulation | Soft Gel Capsule |
| Usage | Erectile Dysfunction |
| Onset of Action | 15-30 minutes |
| Duration | Up to 5 hours |
| Link | More Information |
Pharmacokinetics
The pharmacokinetics of Levitra Super Active involves its absorption, distribution, metabolism, and excretion. Once ingested, the vardenafil 20mg in the formulation rapidly enters the bloodstream. Its soft gel form aids in quick absorption, allowing the active compound to reach peak plasma levels within 30 to 60 minutes. The bioavailability is approximately 15%. Vardenafil is primarily metabolized by hepatic enzymes, predominantly CYP3A4, with minor contributions from CYP3A5 and CYP2C. The elimination half-life ranges from 4 to 5 hours. Excretion occurs primarily through the fecal route, with a smaller proportion eliminated via urine.
Mechanism of Action
Levitra Super Active enhances erectile function by modulating the nitric oxide (NO) pathway. During sexual arousal, NO is released in the corpus cavernosum of the penis. This leads to increased levels of cyclic guanosine monophosphate (cGMP), resulting in smooth muscle relaxation and increased blood flow. Vardenafil 20mg acts as a potent inhibitor of phosphodiesterase type 5 (PDE5), an enzyme responsible for cGMP degradation. By inhibiting PDE5, vardenafil maintains elevated cGMP levels, thus facilitating an erection. This effect occurs only with sexual stimulation.
Levitra Super Active Precautions
Prior to initiating therapy with Levitra Super Active, it is crucial to evaluate cardiovascular status, as sexual activity poses a risk in individuals with heart disease. Those with a history of stroke, myocardial infarction, or life-threatening arrhythmias should exercise caution. The risk of priapism necessitates caution in patients predisposed to prolonged erections, such as those with sickle cell anemia, multiple myeloma, or leukemia. Liver and kidney impairment can alter drug clearance, necessitating dosage adjustments.
Cautions with Other Medicines
Levitra Super Active has significant interactions with nitrates, leading to a dangerous drop in blood pressure. It should not be used in conjunction with other PDE5 inhibitors. Caution is advised when taken alongside alpha-blockers, which can also lead to hypotension. Concomitant use with drugs that strongly inhibit CYP3A4, such as ketoconazole or ritonavir, may increase vardenafil levels, necessitating dose adjustments. Antihypertensives and some antiarrhythmics may interact adversely with vardenafil.
Effects of Levitra Super Active
Levitra Super Active effectively enhances erectile response, offering a more rapid onset compared to traditional tablets. Users typically experience improvements in their ability to achieve and maintain an erection. The formulation’s fast-acting nature makes it suitable for on-demand use. While effective, it may cause side effects such as headache, flushing, and nasal congestion. Rare but serious effects include vision changes and sudden hearing loss, warranting immediate medical attention.
Is Non-prescription Levitra Super Active Available?
Levitra Super Active is a prescription medication. It requires healthcare provider evaluation and authorization. This ensures the drug’s safety and efficacy for individual patients. There are no legal avenues to obtain it over the counter. Unauthorized online purchases pose significant risks due to potential counterfeit products and lack of medical supervision. Patients should consult healthcare providers for legitimate access to vardenafil 20mg, ensuring proper dosage and monitoring.
| Comparison | Levitra Super Active | Standard Levitra |
|---|---|---|
| Onset | 15-30 minutes | 30-60 minutes |
| Form | Soft Gel Capsule | Tablet |
| Duration | Up to 5 hours | Up to 4 hours |
Data source:
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